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The funding for the HCV database project has stopped, and this website and the HCV immunology database are no longer maintained. The site will stay up, but problems will not be fixed. The database was last updated in September 2007. The HIV immunology website contains the same tools, and may be usable for non-HCV-specific analyses. For new epitope information, users of this database can try the Immuno Epitope Database (http://www.immuneepitope.org). More information is here.

All HCV T-Helper (Th) epitopes mapped to within a region of 21 amino acids or less are indicated on the protein epitope maps. The location and HLA restriction elements of Th epitopes are indicated on protein sequences of H77. These maps are meant to provide the relative location of defined epitopes on a given protein, but the H77 sequence may not actually carry the epitope of interest, as it may vary relative to the sequence for which the epitope was defined. Epitopes with identical boundaries and HLA fields are included in the maps only once. If one laboratory determines HLA presenting molecules at the serotype level (example: A2) and another at the genotype level (example: A*0201) both will be included in the map. MHC specificities are indicative of the host species; when no MHC presenting molecule is defined, the host species is noted.

E1 Helper Epitope Map

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