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The funding for the HCV database project has stopped, and this website and the HCV immunology database are no longer maintained. The site will stay up, but problems will not be fixed. The database was last updated in September 2007. The HIV immunology website contains the same tools, and may be usable for non-HCV-specific analyses. For new epitope information, users of this database can try the Immuno Epitope Database (http://www.immuneepitope.org). More information is here.

Antibody Epitope Summary

Download antibody epitope summary.

This is a list of all HCV Antibody binding sites mapped to within a region of 21 amino acids or less. The protein, MAb name, H77 location, and host species are provided. Identical entries are shown only once. The epitope sequence is a link to the database which will provide deatils of all epitopes containing that sequence.

Epitope MAb Name Protein H77 Location Species
MSTNPKPQRKTKRNTNR AF6 Core 1-17 human
MSTNPKPQRKTKRNTNR HP6014 Core 1-17 human
MSTNPKPQRKTKRNTNR NL16 Core 1-17 human
MSTNPKPQRKTKRNTNR RJ4 Core 1-17 human
MSTNPKPQRKTKRNTNR ZG4 Core 1-17 human
PQRKTKRNTNRR polyclonal Core 7-18 human
RPQDVKFP 2C6F6 Core 18-25 mouse
RPQDVKFP 7G12A8 Core 18-25 mouse
RPQDVKFP 7H2D4 Core 18-25 mouse
QIVGGVYL 14C12F5 Core 29-36 mouse
QIVGGVYL 19D9D6 Core 29-36 mouse
QIVGGVYL 1G6C12 Core 29-36 mouse
QIVGGVYL 27D5G5 Core 29-36 mouse
VYLLPR UI/F10 Core 34-39 human
VYLLPRRGPRLG B12.F8 Core 34-45 human
PRGRRQPI 2G9A7 Core 58-65 mouse
PRGRRQPI 2H12H9 Core 58-65 mouse
YEVRNVSGVYH H-111 E1 192-202 human
YEVRNVSGIYHVTNDCSNS 159 E1 192-210
SSGLYHVTNDC A4 E1 197-207 mouse
SIVYEAA 3D5/C3 E1 211-217
RHWTTQGCNC D32.10 E1 297-306 mouse
SGHRMAWDMMMNWSPTT UI/F30 E1 314-330 human
SGHRMAWDMMMNWSPTT UI/F31 E1 314-330 human
SGHRMAWDMMMNWSPTT UI/F32 E1 314-330 human
SGHRMAWDMMMNWSPTT UI/F33 E1 314-330 human
ETHVTGGS 6/16 E2 384-391 rat
ETHVTGGS 6/82a E2 384-391 rat
ETHVTGGS 7/59 E2 384-391 rat
TAGLVGLLTPGA ? 9/27 E2 396-407 rat
SQKIQLVNTNGSWHI polyclonal E2 408-422 human
QLINTNGSWHIN 3/11 E2 412-423 rat
QLINTNGSWHVN AP33 E2 412-423 mouse
GSWHINRTALNCND H E2 418-431 mouse
SLNTGWLAGLFY 1/39 E2 432-443 rat
GWLAGLFY 2/69a E2 436-443 rat
GWLAGLFYHHK 7/16b E2 436-446 rat
GWLAGLFYQHKF ? 11/20c E2 436-447 rat
DFDQGWGP 6/1a E2 464-471 rat
DFDQGWGP AP320 E2 464-471 mouse
DFDQGWGPISYA AP109 E2 464-475 mouse
DFAQGWGPISYA ? AP436 E2 464-475 mouse
PDQRPYCWHYPPKPC D32.10 E2 480-494 mouse
DQRPYCWHYPP 6/41a E2 481-491 rat
PYCWHYPPKPCGIVPA polyclonal E2 484-499 human
SGAPTYSW 3E5-1 E2 522-529
APTYSWGA ? 2/64a E2 524-531 rat
APTYSWGA 9/75 E2 524-531 rat
PPLGNWFG 6/53 E2 544-551 rat
YRLWHYPCT D32.10 E2 613-621 mouse
LDAACNWTRGERCD ALP98 E2 640-653 mouse
CNWTRGER ? ALP11 E2 644-651 mouse
CNWTRGER ? AP266 E2 644-651 mouse
RGERCDLEDRDR ALP1 E2 648-659 mouse
TTMRSPVFTDNS ? 5I NS3 1203-1214 mouse
SSPPAVPQSFQV ? 6L NS3 1214-1225 mouse
GEIPFYGKAIPL ZX10 NS3 1371-1382 mouse
FTGDFDSVIDCN ? 5D NS3 1444-1455 mouse
VLYREF 60H9(9)D10 NS4a 1700-1705 human
VAHDGAGKRVY 5B-3B1 NS5b 2792-2802 mouse
 
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