The funding for the HCV database project has stopped, and this website and the HCV immunology database are no longer maintained. The site will stay up, but problems will not be fixed. The database was last updated in September 2007. The HIV immunology website contains the same tools, and may be usable for non-HCV-specific analyses. For new epitope information, users of this database can try the Immuno Epitope Database (http://www.immuneepitope.org). More information is here.

Binding type MAb ID (Number)

Core

Core N-term AF6 (4015), HP6014 (4016), NL16 (4012), RJ4 (4014), ZG4 (4013), 2D2 (7021), 3D7 (13029), 4F4 (13030), 4G8 (13031)

conformational 14C12F5 (3008), 19D9D6 (2007), 1G6C12 (3010), 27D5G5 (3009), B12.F8 (3023), 2G9A7 (3014), 2H12H9 (3015), 2D2 (7021), 3C4 (13028), 3D7 (13029), 4F4 (13030), 4G8 (13031), 6G11 (13034)

immunodominant region AF6 (4015), HP6014 (4016), NL16 (4012), RJ4 (4014), ZG4 (4013), 2C6F6 (3013), 7G12A8 (3012), 7H2D4 (3011), 14C12F5 (3008), 19D9D6 (2007), 1G6C12 (3010), 27D5G5 (3009), B12.F8 (3023), 2G9A7 (3014), 2H12H9 (3015)

other polyclonal (1), Anti-core (c22c) (7012), UI/F10 (8020), UI/F11 (14026)

E1

E1 N-terminus H-111 (1002)

E1 conserved domain UI/F30 (6011), UI/F31 (6012), UI/F32 (6013), UI/F33 (6014)

conformational D32.10 (9021)

other 159 (11023), polyclonal (7017), A4 (10035), 3D5/C3 (11024)

E2

CD81-binding region D32.10 (9024), 6/41a (11032), 6/53 (11033), D32.10 (9023)

E1E2 association site (WHY) D32.10 (9024), D32.10 (9023)

E2 C-terminus 4D2 (15028), 7B7 (15029)

E2 N-terminus/HVR1 polyclonal (1003)

HVR1 6/82a (11027), 7/59 (11041), 9/27 (11028), 1G2A7 (16031), 9/86a (12032)

HVR2 D32.10 (9024), D32.10 (9023)

conformational 9/27 (11028), D32.10 (9024), D32.10 (9023), 108 (16029), 1H3 (15030), 2F7 (15034), 2H8 (15032), 3F12 (15033), 4D2 (15028), 4F7 (15031), 503 (16028), 7B7 (15029), 9/86a (12032), H2 (11044), H53 (11025), H60 (11042)

other 6/16 (11026), polyclonal (7018), 3/11 (11031), AP33 (12024), H (10038), 1/39 (11035), 2/69a (11037), 7/16b (11030), 11/20c (12033), 6/1a (11034), AP320 (12025), AP109 (12026), AP436 (12031), polyclonal (3025), 3E5-1 (12035), 2/64a (12034), 9/75 (11038), ALP98 (12027), ALP11 (12029), AP266 (12030), ALP1 (12028), 291 (16030), A11 (10036), CBH-11 (10033), CBH-17 (10034), CBH-2 (10024), CBH-4B (10026), CBH-4D (10025), CBH-4G (10027), CBH-5 (10029), CBH-7 (10030), CBH-8C (10031), CBH-8E (10032), I19 (10037), polyclonal (17029)

E1E2

conformational 1A7 (15027), 1B12 (15042), 2C4 (15041), 2G1 (15039), 2H1 (15036), 2H9 (15040), 3E2 (15037), 4E5 (15038), 4F1 (15035)

NS3

c33c (NS3) 5I (13025), 6L (13026), 5D (13027), CM3.B6 (5010)

conformational CM3.B6 (5010)

helicase domain of NS3 ZX10 (5012), 3B1C4 (10023), 12A1H2 (14027)

immunodominant region CM3.B6 (5010)

other Anti-NS3 (c33c) (7013)

NS4a

5-1-1 (NS4) 60H9(9)D10 (4010)

c100-3 (NS4) 60H9(9)D10 (4010)

immunodominant region 60H9(9)D10 (4010)

other Anti-NS4 (5-1-1, type 1) (7015)

NS4b

other Anti-NS4 (c100c) (7014)

NS5a

other Anti-NS5 (7016)

NS5b

conformational 5B-12B7 (7020)

fingers subdomain 5B-12B7 (7020)

other 5B-2A5 (14028), 5B-2A7 (14029), 5B-3F3 (14030), 5B-4C1 (14031)

palm subdomain 5B-12B7 (7020), 5B-3B1 (7019)

thumb subdomain 5B-3B1 (7019)

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